娄红祥教授 当前位置:主页 > 科研团队 >
 

娄红祥,男,1965年3月出生,中共党员,博士,天然药物化学教授,博士生导师。现任山东大学党委常委、副校长。
电话:0531-88382501
传真:0531-88382019
E-mail:louhongxiang@sdu.edu.cn

教育经历:
1985年7月于山东医学院药学系获理学学士学位;1986年于中国药科大学进行研究生课程学习,1988年7月于山东省医学科学院药物研究所获医学硕士学位;1991年7月于沈阳药科大学获理学博士学位

工作经历:
1991年7月山东医科大学药学系任教,先后被聘为副教授、教授;1996年1月任山东医科大学药学系副主任;1997年12月任山东医科大学药学院副院长,其间,1997年3月至1998年11月在日本国立生命工业技术研究所访问研究;1998年11月任山东医科大学药学院院长;2001年1月任山东大学药学院院长;2003年10月任山东大学校长助理、药学院院长;2004年1月任山东大学校长助理、研究生院常务副院长、药学院院长;2005年10月至今任山东大学党委常委、副校长

主要学术兼职
国家重大新药创制中心(山东)主任及理事会理事长;山东大学校学术委员会副主任,药学院学术委员会主任;中国药学会理事会理事,山东药学会理事长,全国高等医学教学会、药学教育研究会第一届理事会常务理事,等。任国家自然科学基金委员会评审专家,山东省医药科技成果鉴定专家等。并任《中草药》、《中国天然药物》、《天然产物研究与开发》、《国外医药-植物药分册》、《中国药物化学杂志》、《亚太传统医药》、《现代药物与临床》、《药学教育》、《齐鲁药事》、《食品与药品》、Journal of  Asian Natural Product  Research、Journal of  Chinese Pharmaceutical Sciences、Phytochemical  Analysis、Chemistry  &  Biodiversity、Drug  Discoveries  &  Therapeutics 和BioScience Trends 等期刊编委。

主要成绩
近5年主要基金项目:
1. 真菌耐受的发生机制及小分子拮抗剂的发现,国家自然基金(No. 81273383)项目负责人,110万,2013年1月-2016年12月
2. 基于鼠李糖凝集素受体为靶点的抗肿瘤糖苷类化合物研究,国家自然基金(No. 81172956)项目负责人,63万,2012年1月-2015年12月
3. 苔藓植物化学成分与生物学意义的研究,国家杰出青年科学基金(No. 30925038)项目负责人,200万,2010年1月-2013年12月
4. 注射用羽苔素-一种新型肿瘤耐药逆转剂的临床前研究,“重大新药创制”科技重大专项课题(No. 2009ZX09102-127),项目负责人,286.79万元,2009年1月-2010年12月
5. 现代色谱-波谱技术在中药质量控制中的应用研究,十一五国家科技支撑计划(No. 2006BAI06A01-05),项目负责人,60 万元,2006年1月—2009年12月
6. 微生物来源免疫抑制剂相关微生物菌株的代谢网络研究,十一五国家科技支撑计划(No. 2007BAI29B02),项目负责人,300万,2007年10 月—2009 年12月
7. 苔藓植物中抗真菌耐药有效成分的高通量发现与衍生物制备,国家自然科学基金重点项目(No. 30730109),项目负责人,160 万元,2008年1月−2011年12月
8. 苔类植物成分抑制真菌生物被膜形成及逆转耐药的研究 国家自然科学基金项目(No. 30672531), 项目负责人,30 万元,2007年1月−2009年12月
9. 原花青素诱导心肌细胞内源性抗氧化剂分子机理和抗氧化性损伤的研究 国家自然科学基金项目(No. 30472072), 项目负责人,17万,2005年1月−2007年12月
10. 苔类植物联苄类化合物抗真菌及逆转真菌耐药机制研究 国家重点基础研究发展计划(973计划)课题(No. 2006CB708512), 项目负责人,70万,2007年1月−2008年12月
11. 苔藓植物新结构联苄类化合物的发现及与微管(蛋白)相互作用研究, 山东省自然科学杰出青年基金(JQ200806), 项目负责人,50万元, 2009年1月—2011年12月
12. 基于糖识别的重大疾病耐药逆转剂的研究,山东省自主创新重大科技专项计划 (No. 2006GG1102023), 项目负责人,200万元,2006年1月—2008年12月

近 5 年主要SCI 论著
1. Li G, Wang HY, Zhu RX, Sun LM, Wang LN, Li M, Li YY,  Liu YQ,  Zhao ZT, Lou  H,Phaeosphaerins A-F, Cytotoxic Perylenequinones from an Endolichenic Fungus, Phaeosphaeria sp. Journal of Natural Products, 2012, 75, 142-147.
2. Li Y, Ma YK, Zhang L, Guo F, Ren L, Yang R, Li Y, Lou HX,In vivo inhibitory effect on the biofilm formation of Candida albicans by liverwort derived riccardin D. PLoS One , 2012, 7(4), e35543.
3. Chang WQ, Li Y, Zhang L, Cheng AX, Lou HX,Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production. PLoS One, 2012, 7(7), e41624.
4. Chang WQ, Li Y, Zhang L, Cheng AX, Liu YQ, Lou HX, Retigeric Acid B Enhances the Efficacy of Azoles Combating the Virulence and Biofilm Formation of Candida albicans. Biological & pharmaceutical bulletin, 2012, 35(10), 1794-801.
5. Liu N, Wang S, Lou HX, A new pimarane-type diterpenoid from moss Pseudoleskeella papillosa (Lindb.) Kindb. Acta Pharmaceutica Sinica B, 2012, 2(3), 256-259.
6. Cui CZ, Wen XS, Cui M, Gao J, Sun B, Lou HX, Synthesis of solasodine glycoside derivatives and evaluation of their cytotoxic effects on human cancer cells. Drug Discoveries & Therapeutics, 2012, 6(1), 9-17.
7. Fan PH, Zhao LX, Hostettmann K, Lou HX, Chemical constituents of Asplenium ruta-muraria L. Natural product research, 2012, 26(15), 1413-1418.
8. Zhang L, Chang WQ, Sun B, Groh M, Speicher A, Lou HX. Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans. PLOS ONE, 2011, 6, e28953.
9. Wang YY, Gao J, Gu GF, Li G, Cui C, Sun B, Lou HX. In situ RBL receptor visualization and its mediated anticancer activity for solasodine rhamnosides. ChemBioChem, 2011, 12, 2418-2420.
10. Xie CF, Zhu RX, Qu JB, Wang LN, Guo DX, Yu WT, Liu CB, Lou HX. Stereochemical Investigation of Macrocyclic Bisbibenzyls with a Stereogenic Center at One of the Ethylene Bridges. Helvetica Chimica Acta, 2011, 94, 2077-2086.
11. Wang J, Tan HN, Yu AH, Ling PX, Lou HX, Zhai GX, Wu J. Preparation of Chitosan-Based Nanoparticles for Delivery of Low Molecular Weight Heparin. Journal of Biomedical Nanotechnology. 2011, 7, 696-703.
12. Sun CC, Zhang YS, Xue X, Cheng YN, Liu HP, Zhao CR, Lou HX, Qu XJ. Inhibition of angiogenesis involves in anticancer activity of riccardin D, a macrocyclic bisbibenzyl, in human lung carcinoma. European Journal of Pharmacology. 2011, 667, 136-143.
13. Cui M, Zhang YH, Liu SS, Lou HX. 1-Oxoeudesnn-11(13)-ene-12,8 alpha-lactone-induced Apoptosis via ROS Generation and Mitochondria Activation in MCF-7 Cells. Archives of Pharmacal Research. 2011, 34, 1323-1329.
14. Li X, Zhao Y, Ji M, Liu SS, Cui M, Lou HX. Induction of actin disruption and downregulation of P-glycoprotein expression by solamargine in multidrug-resistant K562/A02 cells. Chinese Medical Journal. 2011, 124, 2038-2044.
15. Lou HY, Fan PH, Perez RG, Lou HX. Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-beta-induced neuronal cell death. Bioorganic & Medicinal Chemistry. 2011, 19: (13), 4021-4027.
16. Wang SQ, Li X, Wang XN, Wei NN, Lou HX. Coumarins from Cicuta virosa and their modulating effects on multidrug-resistant (MDR) tumors. Phytochemistry Letters. 2011, 4, 97-100.
17. Wu CS, Lin ZM, Wang LN, Guo DX, Wang SQ, Liu YQ, Yuan HQ, Lou HX. Phenolic compounds with NF-kappa B inhibitory effects from the fungus Phellinus baumii. Bioorganic & Medicinal Chemistry Letters. 2011, 21, 3261-3267.
18. Chang WQ, Wu XZ, Cheng AX, Zhang L, Ji M, Lou HX. Retigeric acid B exerts antifungal effect through enhanced reactive oxygen species and decreased cAMP. Biochimica et Biophysica Acta (BBA) - General Subjects. 2011, 1810, 569-576.
19. Sun LM, Zhao Y, Yuan HQ, Li X, Cheng AX, Lou HX. Solamargine, a steroidal alkaloid glycoside, induces oncosis in human K562 leukemia and squamous cell carcinoma KB cells. Cancer Chemotherapy and Pharmacology. 2011, 67, 813-821.
20. Xie CF, Sun B, Guo DX, Gao J, Qu JB, Lou HX. Terpenoids from the Chinese Liverwort Chiloscyphus polyanthus. Helvetica Chimica Acta, 2011, 94, 534-538.
21. Wang XL, Kong F, Shen T, Young CYF, Lou HX, Yuan HQ. Sesquiterpenoids from myrrh inhibit androgen receptor expression and function in human prostate cancer cells. Acta Pharmacologica Sinica. 2011, 32, 338-344.
22. Li X, Wu WK, Sun B, Cui M, Liu S, Gao J, Lou HX. Dihydroptychantol A, a macrocyclic bisbibenzyl derivative, induces autophagy and following apoptosis associated with p53 pathway in human osteosarcoma U2OS cells. Toxicol. Appl. Pharmacol. 2011, 251, 146154.
23. Li X, Zhao Y, Wu WKK, Liu SS, Cui M, Lou HX. Solamargine induces apoptosis associated with p53 transcription-dependent and transcription-independent pathways in human osteosarcoma U2OS cells. Life Sciences. 2011, 88, 314-321.
24. Gao Y, Li ZG, Sun M, Guo CY, Yu AH, Xi YW, Cui J, Lou HX, Zhai GX. Preparation and characterization of intravenously injectable curcumin nanosuspension. Drug Delivery. 2011, 18, 131-142.
25. Gao J, Li X, Gu GF, Sun B, Cui M, Ji M, Lou HX. Efficient synthesis of trisaccharide saponins and their tumor cell killing effects through oncotic necrosis. Bioorganic & Medicinal Chemistry Letters. 2011, 21, 622-627.
26. Wang LN, Guo DX, Wang SQ, Wu CS, Rehman MU, Lou HX. Phenolic Glycosides from the Chinese Liverwort Reboulia hemisphaerica. Helvetica Chimica Acta, 2011, 94, 1146-1152.
27. Liu N, Guo DX, Wang YY, Wang LN, Ji M, Lou HX. Aromatic Compounds from the Liverwort Conocephalum japonicum. Natural Product Communications. 2011, 6, 49-52.
28. Wang LN, Xie CF, Zhu XS, Fan PH, Lou HX. Determination of atropisomeric configurations of macrocyclic bisbibenzyls by HPLC-CD/UV and quantum chemical calculations. Journal of Asian Natural Products Research. 2011, 13, 312-318.
29. Guo DX, Zhu RX, Wang XN, Wang LN, Wang SQ, Lin ZM, Lou HX*. Scaparvin A, a novel caged cis-clerodane with an unprecedented C-6/C-11 bond, and related diterpenoids from the liverwort Scapania parva. Org. Lett. 2010, 12 (19): 44044407.
30. Guo DX, Xiang F, Wang XN, Yuan HQ, Xi GM, Wang YY, Yu WT, Lou HX*. Labdane diterpenoids and highly methoxylated bibenzyls from the liverwort Frullania inouei. Phytochemistry, 2010, 71 (13): 15731578.
31. Wang SQ, Han XZ, Li X, Ren DM, Wang XN, Lou HX*. Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. Bioorg. Med. Chem. Lett. 2010, 20(22): 6411-6415.
32. Sun LM, Zhao Y, Yuan HQ, Li X, Cheng AX, Lou HX*. Solamargine, a steroidal alkaloid glycoside, induces oncosis in human K562 leukemia and squamous cell carcinoma KB cells. Cancer Chemother. Pharmacol. 2010, DOI 10.1007/s00280-010-1387-9.
33. Shen J, Li G, Liu QL, He QW, Gu JH, Shi YQ, Lou HX*. Marchantin C: a potential anti-invasion agent in glioma cells. Cancer. Bio. Ther., 2010, 9(1): 33-39.
34. Xi GM, Sun B, Jiang HH, Kong F, Yuan HQ, Lou HX*. Bisbibenzyl derivatives sensitize vincristine-resistant KB/VCR cells to chemotherapeutic agents by retarding P-gp activity. Bioorg. Med. Chem, 2010, 18(18): 67256733.
35. Yuan HQ, Young CY F, Tian YY, Liu ZF, Zhang MY, Lou HX*. Suppression of the androgen receptor function by quercetin through protein–protein interactions of Sp1, c-Jun, and the androgen receptor in human prostate cancer cells,Mol. Cell. Biochem., 2010, 339:253–262.
36. Sun LM, Zhao Y, Li X, Yuan HQ, Cheng AX, Lou HX*. A lysosomal–mitochondrial death pathway is induced by solamargine in human K562 leukemia cells. Toxico. in Vitro, 2010, 24(6): 15041511.
37. Wu XZ, Chang WQ, Cheng AX, Sun LM, Lou HX*. Plagiochin E, an antifungal active macrocyclic bis(bibenzyl), induced apoptosis in Candida albicans through a metacaspase-dependent apoptotic pathway. Biochim. Biophys. Acta -General Subjects, 2010, 1800(4): 439447.
38. Xu AH,Hu ZM, Qu JB, Liu SM, Syed  A K A, Yuan HQ, Lou HX*. Cyclic bisbibenzyls induce growth arrest and apoptosis of human prostate cancer PC3 cells,Acta. Pharmacol. Sinica., 2010, 31: 609–615
39. Zhao Y, Sun LM, Wang XN, Shen T, Ji M, Lou HX*. Hydroxylation of Diosgenin by Absidia coerulea,Nat. Prod. Commun., 2010, 5(3):373-376.
40. Xie CF, Qu JB, Wu XZ, Liu N, Ji M, Lou HX*. Antifungal macrocyclic bis(bibenzyls) from the Chinese liverwort Ptagiochasm intermedlum L., Nat. Prod. Res., 2010, 24: 6, 515 — 520.
41. Fan PH, Hostettmann K, Lou HX*. Allelochemicals of the invasive neophyte Polygonum cuspidatum Sieb. &Zucc. (Polygonaceae), Chemoecology, 2010, 20: 223-227.
42. Li X, Sun B, Zhu CJ, Yuan HQ, Shi YQ Gao J, Li SJ, Lou HX*. Reversal of p-glycoprotein-mediated multidrug resistance by macrocyclic bisbibenzyl derivatives in adriamycin-resistant human myelogenous leukemia (K562/A02) cells. Toxicol. In Vitro, 2009, 23, 29-36.
43. Sun LM, Sun SJ, Cheng AX, Wu XZ, Zhang Y, Lou HX*. In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans. Antimicrob. Agents Chemother., 2009, 53, 1586-1591.
44. Shi YQ, Zhu CJ, Yuan HQ, Li BQ, Gao J, Qu XJ, Sun B, Cheng YN, Li S, Li X, Lou HX*. Marchantin C, a novel microtubule inhibitor from liverwort with anti-tumor activity both in vivo and in vitro. Cancer Lett., 2009, 276, 160-170.
45. Sun LM, Lv BB, Cheng AX, Wu XZ, Lou HX*. The effect of plagiochin E alone and in combination with fluconazole on the ergosterol biosynthesis of Candida albicans. Biol. Pharm. Bull., 2009, 32, 36-40.
46. Wang XN, Zhang HJ, Ren DM, Ji M, Yu WT, Lou HX*. Lobarialides A–C, antifungal triterpenoids from the lichen Lobaria kurokawae. Chem Biodivers., 2009, 6, 746-753.
47. Shen T, Wang XN, Lou HX*. Natural stilbenes: an overview. Nat. Prod. Rep., 2009, 26, 916-935.
48. Shen T, Wan WZ, Wang XN, Yuan HQ, Ji M, Lou HX*. A triterpenoid and sesquiterpenoids from the resinous exudates of Commiphora myrrha. Helv. Chim. Acta, 2009, 92, 645-652.
49. Wang SQ, Ren DM, Xiang F, Wang XN, Zhu CJ, Yuan HQ, Sun LM, Lv BB, Sun XJ, Lou HX*. Dracotanosides A−D, spermidine glycosides from Dracocephalum tanguticum: Structure and amide rotational barrier. J. Nat. Prod, 2009, 72, 1006-1010.
50. Xie CF, Yuan HQ, Qu JB, Xing J, Lv BB, Wang XN, Ji M, Lou HX*. Biocatalytic production of acyclic bis[bibenzyls] from dihydroresveratrol by Crude Momordica charantia Peroxidase. Chem. Biodiver. 2009, 6, 1193-1201. 
51. Guo DX, Du Y, Wang YY, Sun LM, Qu JB, Wang XN, Lou HX*. Secondary Metabolites from the Liverwort Ptilidium pulcherrimum. Nat. Prod. Commun, 2009, 4, 1319-1322.
52. Wu XZ, Cheng AX, Sun LM, Sun SJ, Lou HX*. Plagiochin E, an antifungal bis(bibenzyl), exerts its antifungal activity through mitochondrial dysfunction-induced reactive oxygen species accumulation in Candida albicans. Biochem.et Biophy. acta-Genenral Subjects, 2009, 1790, 770-777.
53. Cheng, AX; Sun, LM; Wu, XZ, Lou HX*. The inhibitory effect of a macrocyclic bisbibenzyl riccardin D on the biofilms of Candida albicans. Bio. Pharm. Bull., 2009, 32, 1417-1421.
54. Sun, B; Yuan, HQ; Xi, GM, Ma YD, Lou HX*. Synthesis and multidrug resistance reversal activity of dihydroptychantol A and its novel derivatives. Bioorg. Med. Chem. 2009, 17, 4981-4989.
55. Xie CF, Lou HX*. Secondary metabolites in bryophytes: An ecological aspect. Chem. Biodivers., 2009, 6, 303-312.
56. Gao J, Li X, Lv BB, Sun B, Zhu CJ, Lou HX*. LC-DAD/MS/MS Detection of Macrocyclic Bisbibenzyls from the Liverwort Reboulia hemisphaerica and the Cell-based Screening of their microtubule inhibitory effects. Chin J. Nat. Med., 2009, 7, 123-128.
57. Shi YQ, Liao YX, Qu J, Yuan HQ, Li S, Qu JB, Lou HX*. Marchantin C, a macrocyclic bisbibenzyl, induces apoptosis of human glioma A172 cells. Cancer Lett. 2008, 262, 173-182.
58. Guo XL, Leng P, Yang Y, Yu LG, Lou HX*. Plagiochin E, a botanic-derived phenolic compound, reverses fungal resistance to fluconazole relating to the efflux pump. J Appl. Microb. 2008, 104, 831-838.
59. Han  XZ,  Ren  DM,  Fan  PH,  Shen  T,  Lou  HX*.  Protective  effects  of  naringenin-7-O-glucoside  on  doxorubicin-induced apoptosis in H9C2 cells. Eur. J Pharmacol. 2008, 581, 47-53.
60. Han XZ, Pan JH, Ren DM, Cheng YN, Fan PH, Lou HX*. Naringenin-7-O-glucoside protects against doxorubicin-induced toxicity in H9c2 cardiomyocytes by induction of endogenous antioxidant enzymes.  Food Chem. Toxicol. 2008, 46, 3140-3146.
61. Xing J, Lv BB, Xie CF, Qu JB, Lou HX*. Liquid chromatography–tandem mass spectrometry assay for the quantitation of plagiochin E and its main metabolite plagiochin E glucuronides in rat plasma. J Pharm. Biomed. Anal. 2008, 47, 949-953.
62. Du Y, Lou HX*.  Catechin  and  proanthocyanidin  B4  from  grape  seeds  prevent  doxorubicin-induced  toxicity  in cardiomyocytes. Eur. J Pharmacol. 2008, 591, 96-101.
63. Qu JB, Zhu RL, Zhang YL, Guo HF, Wang XN, Xie CF, Yu WT, Ji M,  Lou  HX*. ent-Kaurane diterpenoids from the liverwort Jungermannia atrobrunnea. J. Nat. Prod. 2008, 71, 1418-1422.
64. Xie CF, Lou HX*. Chemical constituents from the Chinese bryophytes and their reversal of fungal resistance. Curr. Org. Chem. 2008, 12, 619-628.
65. Yuan HQ, Kong F, Wang XL, Young CYF, Hu XY, Lou HX*.  Inhibitory effect of acetyl-11-keto-β-boswellic acid on androgen receptor by interference of Sp1 binding. Biochem. Pharmacol. 2008, 75, 2112-2121.
66. Ren DM, Guo HF, Yu WT, Wang SQ, Ji M, Lou  HX*. Stereochemistry of flavonoidal alkaloids from Dracocephalum rupestre. Phytochemistry 2008, 69, 1425-1433.
67. Sun JY, Lou HX, Dai SJ, Xu H, Zhao F, Liu K. Indole alkoloids from Nauclea officinalis with weak antimalarial activity. Phytochemistry 2008, 69, 1405-1410.
68. Shi YQ, Qu XJ, Liao YX, Xie CF, Cheng YN, Li S, Lou HX*, Reversal effect of a bisbibenzyl plagiochin E on multidrug resistance in adriamycin-resistant K562/A02 cells. Eur. J Pharmacol. 2008, 584, 66-71.
69. Shen T, Lou HX*. Bioactive constituents of Myrrh and Frankincense, two simultaneously prescribed gum resins in Chinese traditional medicine. Chem. Biodiver. 2008, 5, 540-553.
70. Shen T, Yuan  HQ, Wan WZ, Wang  XL, Wang  XN,  Ji  M, Lou  HX*.  Cycloartane-type triterpenoids  from  the  resinous exudates of Commiphora opobalsamum. J Nat. Prod. 2008, 71, 81-86.
71. Wu XZ, Cheng AX, Sun LM, Lou HX*. Effect of plagiochin E, an antifungal macrocyclic bis(bibenzyl), on chitin synthesis of cell wall in Candida albicans. Acta Pharmacol. Sinica 2008, 29, 478-485.
72. Ren  DM,  Qu  Z,  Wang  XN,  Shi  J,  Lou  HX*.  Simultaneous  determination  of  nine  major  active  compounds  in Dracocephalum rupestre by HPLC. J Pharm. Biomed. Anal. 2008, 48, 1441-1445.
73. Du Y, Villeneuve NF, Wang XJ, Sun Z, Chen WM, Li JX, Lou HX, Wong PK, Zhang DD. Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. Environ. Health Perspect. 2008, 116, 1154-1161.
74. Qu JB, Xie CF, Ji M, Shi YQ, Lou HX*. Water-soluble constituents from the liverwort Marchantia polymorpha. Helv. Chim. Acta 2007, 90, 2109-2115.
75. Liu XH, Lou HX*. Synthesis of monoterpene alkaloid derivatives from the iridoid glucoside geniposide. Nat. Prod. Res. 2007, 21, 1157-1164.
76. Han XZ, Shen T, Lou HX*. Dietary polyphenols and their biological significance. Int. J Mol. Sci. 2007, 8, 950-988.
77. Sun JY, Lou HX, Xu H, Dai SJ, Liu K. Two new indole alkaloids from Nauclea officinalis. Chin. Chem. Lett. 2007, 18, 1084-1086.
78. Yu BB, Han XZ, Lou HX*. Oligomers of resveratrol and ferulic acid prepared by peroxidase-catalyzed oxidation and their protective effects on cardiac injury. J Agr. Food Chem. 2007, 55, 7753-7757.
79. Ren DM, Guo HF, Wang SQ, Lou HX*. Separation and structure determination of two diastereomeric pairs of enantiomers from  Dracocephalum  rupestre  by  high-performance  liquid  chromatography  with  circular  dichroism  detection.  J Chromatogr A 2007, 1161, 334-337.
80. Xing J, Xie CF, Qu JB, Guo HF, Lv BB, Lou HX*. Rapid screening for bisbibenzyls in bryophyte crude extracts using liquid chromatography/tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21, 2467-2476.
81. Xing J, Xie CF, Lou HX*. Recent applications of liquid chromatography-mass spectrometry in natural products bioanalysis. J Pharm. Biomed. Anal. 2007, 44, 368-378.
82. Qu JB, Xie CF, Guo HF, Yu WT, Lou HX*. Antifungal dibenzofuran bis(bibenzyl)s from the liverwort Asterella angusta. Phytochemistry 2007, 68, 1767-1774.
83. Zhao GS, Wang C, Liu C, Lou HX*. New developments in diketo-containing inhibitors of HIV-1 integrase. Mini-Rev. Med. Chem. 2007, 7, 707-725.
84. Shen T, Wan WZ, Yuan HQ, Kong F, Guo HF, Fan PH, Lou HX*. Secondary metabolites from Commiphora opobalsamum and their antiproliferative effect on human prostate cancer cells. Phytochemistry 2007, 68, 1331-1337.
85. Fang L, Guo HF, Lou HX*. Three new bibenzyl derivatives from the Chinese liverwort Marchantia polymorpha L. Helv. Chim. Acta 2007, 90, 748-752.
86. Guo HF, Xing J, Xie CF, Qu JB, Gao YH, Lou  HX*. Study of bis(bibenzyls) in bryophytes using electron ionization time-of-flight and electrospray ionization triple-quadrupole mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21, 1367-1374 .
87. Zhao GS, Liu C, Wang R, Song DD, Wang XB, Lou  HX, Jing YK. The synthesis of alpha,beta-unsaturated carbonyl derivatives with the ability to inhibit both glutathione S-transferase P1-1 activity and the proliferation of leukemia cells. Bioorg. Med. Chem. 2007, 15, 2701-2707.
88. Zhan TR, Lou HX*.  Synthesis of azole nucleoside analogues of D-pinitol as potential antitumor agents. Carbhyd. Res. 2007, 342, 865-869.
89. Xie CF, Qu JB, Sun B, Guo HF, Lou HX*. Dumhirone A, an unusual phenylethyl cyclohexadienone from the Chinese liverwort Dumortiera hirsuta. Bichem. Syst. Ecol. 2007, 35, 162-165.
90. Du  Y,  Guo  HF,  Lou  HX*.  Grape  seed  polyphenols  protect  cardiac  cells  from  apoptosis  via  induction  of  endogenous antioxidant enzymes. J Agr. Food Chem. 2007, 55, 1695-1701.
91. Ma B, Lu ZQ, Guo HF, Lou HX*. Rearranged calamenene and eudesmane sesquiterpenoids from two Chinese liverworts. Helv. Chim. Acta. 2007, 90, 52-57.
92. Ma B, Guo HF, Lou HX*. A new lignan and two eudesmanes from Lepidozia vitrea. Helv. Chim. Acta. 2007, 90, 58-62.
93. Zhan  TR,  Ma  YD,  Fan  PH,  Ji  M,  Lou  HX*.  Synthesis  of  4/5-deoxy-4/5-nucleobase  derivatives  of  3-O-methyl-D- chiroinositol as potential antiviral agents. Chem. Biodiver. 2006, 3, 1126-1137.
94. Zhang HJ, Guo HF, Lou HX*.  Secondary metabolites from the Chinese lichen Sticta nylanderiana A. Z.. Biochem. Syst. Ecol. 2006, 34, 760-762.
95. Ma ST, Lou HX*. An efficient synthesis of ethyl 7-chloro-6-fluoro-1-methyl- 4-oxo-1,4-dihydro- [1,3]thiazeto [3,2-a] quinoline-3-carboxylate as intermediate of the prulifloxacin containing tricyclic fluoroquinolone. Chin. Chem. Lett. 2006, 17, 714-716.
96. Lu ZQ, Fan PH, Ji M, Lou HX*.  Terpenoids and bisbibenzyls from Chinese liverworts Conocephalum conicum and Dumortiera hirsuta. J Asian Nat. Prod. Res. 2006, 8, 187-192.
97. Liu AC, Lou HX*, Zhao LX, Fan PH. Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin. J Pharm. Biomed. Anal. 2006, 40, 720-727.
98. Niu C, Qu JB, Lou HX*. Antifungal bis[bibenzyls] from the Chinese liverwort Marchantia polymorpha L. Chem. Biodiver. 2006, 3, 34-40.
99. Li ZJ, Lou HX*, Yu WT, Fan PH, Ren DM, Ma B, Ji M. Structures and absolute configurations of three 7,8-secolabdane diterpenes from the Chinese liverwort Pallavicinia ambigua. Helv. Chim. Acta 2005, 88, 2637-2640.
100. Wang XN, Yu WT, Lou HX*. Antifungal constituents from the Chinese moss Homalia trichomanoides. Chem. Biodiver. 2005, 2, 139-145.
101. Sun SJ, Gao YH, Ling X, Lou HX*. The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. Anal. Biochem. 2005, 336, 39-45.

主要专著:
1. 娄红祥, 王小宁. 苔藓植物化学成分研究. 天然产物化学进展; 于德泉, 吴毓林 主编; 化学工业出版社: 北京, 2005年; pp 251300.
2. 娄红祥 主编, 苔藓植物化学和生物学. 北京科学技术出版社: 北京, 2006年; pp 1363..
3. 娄红祥, 范培红. 鞣质. 实用天然有机产物化学; 吴立军 主编; 人民卫生出版社: 北京, 2007年; pp 946-983.
4. 娄红祥, 质谱,有机化合物波谱解析, 吴立军 主编;中国医药科技出版社:北京,2009年;pp220-299.
5. 娄红祥 译. 药用天然产物生物合成, 化学工业出版社, 2008. Paul M Dewick, Medicinal Natural Products, A Biosynthetic Approach, 2nd Edition, Wiley-VCH, 2001.

授权专利:
1. 娄红祥, 翟光喜, 孙隆儒. 葛根素口服制剂及其制备方法, 专利号: ZL02135329.8; 2005 年 6 月 15 日.
2. 娄红祥, 任冬梅, 翟光喜. 一种治疗心脑血管系统疾病的总黄酮及其制备方法与应用, 专利号: ZL02135573.8; 2005 年11 月 23 日.
3. 娄红祥,  牛冲,  范培红.  联苄类化合物 13,13'-O-异丙叉基片叶苔素 D  及其提取分离方法与应用,  专利号: ZL200410036044.6; 2006 年 6 月 28 日.
4. 娄红祥, 刘安昌, 范培红. 姜黄素磷脂复合物及其制备方法, 专利号: ZL200410036402.3; 2006 年 11 月 8 日.  
5. 娄红祥, 刘丽娟, 范培红. 乙酰水杨酰基葛根素衍生物及其制备方法与应用, 专利号: ZL200410036070.9; 2007 年 5 月9 日.
6. 娄红祥, 牛冲, 范培红. 一种联苄类化合物羽苔素 E 及其提取分离方法与应用, 专利号: ZL200410036045.0; 2007 年 1月 17 日.
7. 娄红祥,  刘小红,  范培红.  一种栀子苷元石杉碱甲还原胺化产物及其制备方法与应用,  专利号:  ZL200610042130.7; 2007 年 10 月 31 日.
8. 娄红祥,  詹天容,  马玉道,  范培红.  一组六元碳环核苷类似物及其合成方法和在抗病毒方面的应用,专利号: ZL200610042184.3; 2008 年 8 月 20 日.
9. 娄红祥,李洁,范培红.  一种丹酚酸黄连素复盐及其制备方法与应用,专利号:ZL200410036480.3;2009年6月17日.


受邀参加主要国际会议
1. IAB World Bryology Conference 2007, Kuala Lumpur, Malaysia, July 23-27, 2007. (大会报告)
应世界苔藓植物化学研究最优秀的科学家,日本德岛文理大学 Yoshinori Asakawa 教授的邀请,参加在马来西亚召开的世界苔藓大会。其评价为:“You are undoubtedly one of the top scientists on bryophyte chemistry, I would like to invite you as one of the four special speakers in this session…”。
2. ISDNP Conference on Natural Products, Leysin, Switzerland, May 28-31, 2006. (大会报告)
应大会组委会主席,瑞士日内瓦大学 Kurt Hostettmann 教授邀请参会并作大会报告。
3. IOCD  International  Symposium/Biology,  Chemistry,  Pharmacology  and  Clinical Studies of Asian Plants, Surabaya, Indonesia, April 9-11, 2007. (大会报告)
4. 应大会组委会主席,瑞士日内瓦大学 Kurt Hostettmann 教授邀请参会并作大会报告。 International Congress and 2009 Annual Meeting of the Society for Medicinal Plant Research, Geneva, Switzerland, August 16-20, 2009. (特邀报告)

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